Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp375 | Other diseases of bone and mineral metabolism | ECTS2014

Osteoprotegerin and bone-like vascular calcification are predictive markers of vulnerable carotid plaques

Heymann Marie Francoise , Davaine Jean Michel , Laperine Olivier , Merlini Thierry , Guyomarch Beatrice , Chatelais Mathias , Guilbaud Florian , Brennan Meadhbh Aine , Heymann Dominique , Goueffic Yann

Vascular calcification has a marked impact on arterial heterogeneity and plaque stability. Based on a cohort of 116 patients (carotid and femoral endarterectomies), the aim of the present study was to determine the influence of the bone-like vascular calcification and of osteoprotegerin (OPG) on plaque stability.Seventy-three carotid and 43 femoral plaques along with plasma were harvested and analyzed in a single center study. The presence of osteoid met...